Laboratory of Natural Product Chemistry

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NATURAL PRODUCT TOTAL SYNTHESIS

Natural product total synthesis provides a platform to access complex and privileged architectures with unique target-specific activities. Our research allows us to study biosynthetic pathways, modulate biological function, and explore chemical diversity for the purposes of efficient access to complex scaffolds and medicinally relevant analogs. 

NATURAL PRODUCT BIOSYNTHESIS

We address the antibiotic resistance crisis through the study of molecular mechanisms of action and the characterization of biosynthetic pathways. Our research employs chemical and synthetic biology as tools to answer questions of how microorganisms construct complex, biologically active molecules and how these molecules induce antibacterial activity in vivo. ​